The Laurencia Stereochemical Paradox: Chemical Shift Litmus Test, Asymmetric Total Synthesis, and Structural Reassignment of (+)-Itomanallene B

The Laurencia Stereochemical Paradox: Chemical Shift Litmus Test, Asymmetric Total Synthesis, and Structural Reassignment of (+)-Itomanallene B

Itomanallene B-type metabolites have presented a stereochemical paradox, as Laurencia intricata and Laurencia nangii yield epimeric structures despite sharing the same planar connectivity.

Electrochemical Decarboxylative Hydroxylation for the Sustainable Synthesis of Bempedoic Acid

Electrochemical Decarboxylative Hydroxylation for the Sustainable Synthesis of Bempedoic Acid

A sustainable synthesis of bempedoic acid is achieved using electrochemical hydroxylative decarboxylation as the key step.